The tissue distribution of L-ascorbic acid and dehydro-L-ascorbic acid in the guinea pigs injected intravenously with dehydro-L-ascorbic acid.
نویسندگان
چکیده
منابع مشابه
Metabolism of l-ascorbic acid, dehydro-l'ascorbic acid, and diketo-l-gulonic acid in the guinea pig.
The interrelationships of L-ascorbic acid (AsA) and dehydro-L-ascorbic acid (DHA) have been investigated both in viva and in vitro by numerous workers, with especial emphasis upon the conversion of DHA to AsA by the animal body (l-8). The conversion of DHA to diketo-L-gulonic acid (DKA) in vitro has been shown by Herbert and coworkers (3), by Borsook (l), and by Penney and Zilva (6), and this c...
متن کاملL-Ascorbic Acid Peroxidase
Euglena gracilis was found to contain a peroxidase that specifically requires L-ascorbic acid as the natural electron donor in the cytosol. The presence of an oxidation-reduction system metabolizing L-ascorbic acid was demonstrated in Euglena cells. Oxidation of L-ascorbic acid by the peroxidase, and the absence of ascorbic acid oxidase activity, suggests that the system functions to remove H20...
متن کاملPossible Formation of Dehydro-L-ascorbic Acid from 2,3-Diketo-L-gulonic Acid in an Aqueous Solution.
The reaction of 2,3-diketo-L-gulonic acid (DKG), which is one of the important intermediate products in the degradation of L-ascorbic acid (ASA) in both food and biological systems, in an aqueous solution was studied. The formation of a small amount of the γ-lactone, dehydro-L-ascorbic acid (DASA), from DKG was observed. This strongly suggests the chemical possibility of a reverse reaction in D...
متن کاملl-dehydroascorbic acid can substitute l-ascorbic acid as dietary vitamin C source in guinea pigs
Vitamin C deficiency globally affects several hundred million people and has been associated with increased morbidity and mortality in numerous studies. In this study, bioavailability of the oxidized form of vitamin C (l-dehydroascorbic acid or DHA)-commonly found in vitamin C containing food products prone to oxidation-was studied. Our aim was to compare tissue accumulation of vitamin C in gui...
متن کاملL-Ascorbic acid degradation by bacteria. VIII. All the pathway in the L-ascorbic acid metabolism.
The medium used contained 3g of substrate, 150ml of 1/15M phosphate buffer and 150ml of sterile distilled water. 0.5g (dry weight) of the adapted cells was added to the medium and the whole was incubated at 30•‹ for 20 hours. For detecting the intermediate products, paper chromatography was chiefly used. For developing the nonvolatile acids, n-butanol-acetic acid-water (4:1:1) was used and the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Nutritional Science and Vitaminology
سال: 1986
ISSN: 0301-4800,1881-7742
DOI: 10.3177/jnsv.32.259